CD11b antibodies, human

CD11b antibodies, human

Clone: REA713
Clone REA713 recognizes the human CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on natural killer (NK) cells and some activated lymphocytes as well as on microglia in the brain.
Additional information: Clone REA713 displays negligible binding to Fc receptors.

Alternative names

integrin αM, Mac-1 α, Integrin alpha-M, CR3A

Technical specifications

  • Antigen: CD11b
  • Clone: REA713
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: integrin αM, Mac-1 α, Integrin alpha-M, CR3A
  • Entrez Gene ID: 3684, 16409
  • Molecular mass of antigen [kDa]: 126
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon,
    common marmoset (
    Callithrix jacchus
    )
    , pig, porcine
  • Distribution of antigen: myeloid cells, NK cells, microglia, brain, lymphocytes
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates:
Product options: 1
100 µg in 100 µL
CHF  195.00