Anti-IL-8 antibodies, human

Anti-IL-8 antibodies, human

Clone: REA731 | Dilution: 1:50
Clone REA731 recognizes the human IL-8 chemokine, a heterodimer also known as interleukin 8 or CXCL8 (chemokine (C-X-C motif) ligand 8. IL-8 is secreted by macrophages, epithelial cells, airway smooth muscle cells, and endothelial cells. IL-8 plays a role in neutrophil activation, is a potent promoter of angiogenesis, and attracts neutrophils, basophils, and T cells. Clone REA731 recognizes both the 72 and 77 amino acid isoforms of human IL-8.
Additional information: Clone REA731 displays negligible binding to Fc receptors.

Alternative names

Interleukin-8, Emoctakin, GCP-1, MDNCF, MONAP, NAP-1, Protein 3-10C, CXCL8

Technical specifications

  • Antigen: IL-8
  • Clone: REA731
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: Interleukin-8, Emoctakin, GCP-1, MDNCF, MONAP, NAP-1, Protein 3-10C, CXCL8
  • Entrez Gene ID: 3576
  • Molecular mass of antigen [kDa]: 9
  • Distribution of antigen: neutrophils, basophils, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Mukaida, N. et al. (1989) Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8. J. Immunol. 143(4): 1366-1371
    2. Matsushima, K. et al. (1989) Interleukin 8 and MCAF: novel inflammatory cytokines inducible by IL 1 and TNF. Cytokine 1(1): 2-13
    3. Hébert, C. A. et al. (1990) Endothelial and leukocyte forms of IL-8. Conversion by thrombin and interactions with neutrophils. J. Immunol. 145(9): 3033-3040
Product options: 6
for 30
tests
(1)
CHF  100.00
for 100
tests
(1)
CHF  245.00
for 30
tests
(1)
CHF  120.00
for 100
tests
(1)
CHF  290.00
for 30
tests
(1)
CHF  120.00
for 100
tests
(1)
CHF  290.00

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