Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
AMICA1, junctional adhesion molecule-like

Specifications for JAML Antibody, anti-mouse, REAfinity™


Clone REA862 recognizes the mouse JAML antigen, also known as AMICA1 or junctional adhesion molecule-like protein. JAML is a transmembrane protein, which consists of two extracellular immunoglobulin-like domains, a membrane-spanning region, and a cytoplasmic tail involved in activation signaling. JAML is found on γ/δ intraepithelial T cells. The costimulatory molecule JAML binds to its ligands Coxsackie virus and adenovirus receptor (CAR), that leads to cellular proliferation and cytokine and growth factor production.
Additional information: Clone REA862 displays negligible binding to Fc receptors.

Alternative names

AMICA1, junctional adhesion molecule-like

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenAMICA1, junctional adhesion molecule-like
Molecular mass of antigen [kDa]40
Distribution of antigenT cells
Entrez Gene ID270152
RRIDAB_2726744, AB_2726660, AB_2726745, AB_2726661, AB_2726743, AB_2726659

Resources for JAML Antibody, anti-mouse, REAfinity™


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References for JAML Antibody, anti-mouse, REAfinity™


  1. Zen, K. et al. (2005) Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils. Mol. Biol. Cell 16(6): 2694-2703
  2. Witherden, D. A. et al. (2010) The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation. Science 329(5996): 1205-1210

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