CD99 antibodies, human

CD99 antibodies, human

Clone: 3B2/TA8 | Dilution: 1:11
Clone 3B2/TA8 recognizes the human CD99 antigen, a 32 kDa type I single chain transmembrane sialoglycoprotein which is also known as E2 antigen or MIC2. The expression level of CD99 is particularly high in thymocytes, T cells, T cell leukemias and lymphomas, subsets of mature plasma cells in the medullary cord of reactive lymph nodes, pancreatic islet cells, granulosa cells of the ovary, Sertoli cells of the testes, but absent on granulocytes. It is involved in T cell–adhesion processes and in spontaneous rosette formation with erythrocytes. CD99 plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane and it acts at the same site as, but independently of, PECAM1.

Alternative names

HBA71, MIC2, MIC2X, MIC2Y, MSK5X

Technical specifications

  • Antigen: CD99
  • Clone: 3B2/TA8
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: HBA71, MIC2, MIC2X, MIC2Y, MSK5X
  • Entrez Gene ID: 4267
  • Molecular mass of antigen [kDa]: 17
  • Distribution of antigen: T cells, thymocytes, plasma cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Schenkel, A. R. et al. (2002) CD99 plays a major role in the migration of monocytes through endothelial junctions. Nat. Immunol. 3(2): 143-150
    2. Gelin, C. et al. (1989) The E2 antigen, a 32 kd glycoprotein involved in T-cell adhesion processes, is the MIC2 gene product. EMBO J. 8(11): 3253-3259
    3. Edlund, K. et al. (2012) CD99 is a novel prognostic stromal marker in non-small cell lung cancer. Int. J. Cancer 131(10): 2264-2273
Product options: 12
130-104-363

CD99-FITC, human

for 30
tests
(1)
CAD 110.00
130-104-314

CD99-FITC, human

for 100
tests
(1)
CAD 315.00
130-104-364

CD99-PE, human

for 30
tests
(1)
CAD 130.00
130-104-315

CD99-PE, human

for 100
tests
(1)
CAD 370.00
130-104-365

CD99-APC, human

for 30
tests
(1)
CAD 170.00
130-104-316

CD99-APC, human

for 100
tests
(1)
CAD 390.00
for 30
tests
(1)
CAD 195.00
for 100
tests
(1)
CAD 415.00
for 30
tests
(1)
CAD 190.00
for 100
tests
(1)
CAD 430.00
for 30
tests
(1)
CAD 130.00
for 100
tests
(1)
CAD 315.00

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