CD68 antibodies, mouse

CD68 antibodies, mouse

Clone: REA835 | Dilution: 1:50
Clone REA835 recognizes mouse CD68 antigen, also known as macrosialin, which is a heavily glycosylated type I transmembrane protein of the lysosomal-associated membrane protein (LAMP) family. It is expressed on tissue macrophages, Langerhans cells, and at a low density on dendritic cells. Murine CD68 is predominantly intracellular but it is reported that 10–15% of CD68 is expressed on the cell surface as well. Macrosialin functions as a macrophage receptor for oxidized low density lipoprotein.
Additional information: Clone REA835 displays negligible binding to Fc receptors.

Alternative names

Lamp4, SCARD1, gp110, macrosialin

Technical specifications

  • Antigen: CD68
  • Clone: REA835
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Lamp4, SCARD1, gp110, macrosialin
  • Entrez Gene ID: 12514
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: macrophages, dendritic cells, Langerhans cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Smith, M. J. et al. (1987) Differential expression of murine macrophage surface glycoprotein antigens in intracellular membranes. J. Cell. Sci. 87: 113-119
    2. Ramprasad, M. P. et al. (1996) Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein. Proc. Natl. Acad. Sci. U.S.A. 93: 14833-14838
    3. Kurushima, H. et al. (2000) Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages. J. Leukoc. Biol. 67: 104-108
Product options: 20
130-112-855

CD68-FITC, mouse

30 µg in 200 µL (1)
CAD 65.00
130-112-666

CD68-FITC, mouse

150 µg in 1 mL (1)
CAD 215.00
130-112-856

CD68-PE, mouse

30 µg in 200 µL (1)
CAD 75.00
130-112-667

CD68-PE, mouse

150 µg in 1 mL (1)
CAD 250.00
130-112-857

CD68-APC, mouse

30 µg in 200 µL (1)
CAD 110.00
130-112-668

CD68-APC, mouse

150 µg in 1 mL (1)
CAD 435.00
30 µg in 200 µL (1)
CAD 165.00
150 µg in 1 mL (1)
CAD 545.00
30 µg in 200 µL (1)
CAD 205.00
150 µg in 1 mL (1)
CAD 610.00
30 µg in 200 µL (1)
CAD 185.00
150 µg in 1 mL (1)
CAD 535.00
30 µg in 200 µL (1)
CAD 185.00
150 µg in 1 mL (1)
CAD 535.00
30 µg in 200 µL (1)
CAD 190.00
150 µg in 1 mL (1)
CAD 550.00
30 µg in 200 µL (1)
CAD 185.00
150 µg in 1 mL (1)
CAD 535.00
30 µg in 200 µL (1)
CAD 75.00
150 µg in 1 mL (1)
CAD 240.00

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