CD31 antibodies, human

CD31 antibodies, human

Clone: REA730 | Dilution: 1:50
Clone REA730 recognizes the human CD31 antigen, also known as PECAM-1. CD31 is a member of the immunoglobulin superfamily and is involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is a 120–140 kDa single-chain transmembrane glycoprotein expressed on endothelial cells, monocytes, platelets, granulocytes, and several lymphocyte subsets. During maturation of CD4
+
T cells, the expression of CD31 changes: CD4
+
recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture.
Additional information: Clone REA730 displays negligible binding to Fc receptors.

Alternative names

PECAM-1, EndoCAM, GPIIa, PECA1

Technical specifications

  • Antigen: CD31
  • Clone: REA730
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: PECAM-1, EndoCAM, GPIIa, PECA1
  • Entrez Gene ID: 5175
  • Molecular mass of antigen [kDa]: 80
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Newman, P. J. et al. (1990) PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 247(4947): 1219-1222
    2. Stockinger, H. et al. (1990) Molecular characterization and functional analysis of the leukocyte surface protein CD31. J. Immunol. 145(11): 3889-3897
    3. Kimmig, S. et al. (2002) Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195: 789-794
Product options: 18
130-110-806

CD31-FITC, human

for 30
tests
(1)
CAD 105.00
130-110-668

CD31-FITC, human

for 100
tests
(1)
CAD 315.00
130-110-807

CD31-PE, human

for 30
tests
(1)
CAD 130.00
130-110-669

CD31-PE, human

for 100
tests
(1)
CAD 370.00
130-110-808

CD31-APC, human

for 30
tests
(1)
CAD 170.00
130-110-670

CD31-APC, human

for 100
tests
(1)
CAD 390.00
for 30
tests
(1)
CAD 170.00
for 100
tests
(1)
CAD 410.00
for 30
tests
(1)
CAD 205.00
for 100
tests
(1)
CAD 455.00
for 30
tests
(1)
CAD 195.00
for 100
tests
(1)
CAD 415.00
for 30
tests
(1)
CAD 180.00
for 100
tests
(1)
CAD 430.00
for 30
tests
(1)
CAD 180.00
for 100
tests
(1)
CAD 430.00
for 30
tests
(1)
CAD 105.00
for 100
tests
(1)
CAD 315.00

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