CD300f (IREM-1) antibodies, human

CD300f (IREM-1) antibodies, human

Clone: REA1129 | Dilution: 1:50
Clone REA1129 recognizes the human CD300f antigen, also known as immune receptor expressed by myeloid cell 1 (IREM-1), which is a type I transmembrane glycoprotein member of the CD300 family. It is expressed on myeloid cells and in peripheral blood on monocytes and granulocytes. CD300f binds the p85α regulatory subunit of phosphoinositide 3-kinase (PI3K) and can enhance phagocytosis of apoptotic cells.
Additional information: Clone REA1129 displays negligible binding to Fc receptors.

Alternative names

CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM

Technical specifications

  • Antigen: CD300f (IREM-1)
  • Clone: REA1129
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM
  • Entrez Gene ID: 146722
  • Molecular mass of antigen [kDa]: 30
  • Distribution of antigen: myeloid cells, granulocytes, monocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515
  • Selected references

    1. Álvarez-Errico, D. et al. (2004) IREM-1 is a novel inhibitory receptor expressed by myeloid cells. Eur. J. Immunol. 34(12): 3690-3701
    2. Álvarez-Errico, D. et al. (2007) The IREM-1 (CD300f) inhibitory receptor associates with the p85α subunit of phosphoinositide 3-kinase. J. Immunol. 178: 808-816
    3. Choi, S. C. et al. (2011) Cutting edge: mouse CD300f (CMRF-35-like molecule-1) recognizes outer membrane-exposed phosphatidylserine and can promote phagocytosis. J. Immunol. 187(7): 3483-3487
Product options: 14
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CAD 390.00
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CAD 175.00
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CAD 435.00
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CAD 190.00
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CAD 440.00
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CAD 190.00
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CAD 440.00
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tests
(1)
CAD 225.00
for 100
tests
(1)
CAD 565.00

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