CD300e (IREM-2) antibodies, human

CD300e (IREM-2) antibodies, human

Clone: REA1070
Clone REA1070 recognizes the human CD300e, also known as IREM-2, LMIR6, or CMRF35-A5. This 34 kDa activating receptor of the immunglobulin superfamily is expressed on mature myeloid dendritic cells and monocytes and is down-regulated on immature dendritic cells (DCs). CD300e interacts with DAP-12, which mediates acivating signals. It is reported that the alloreactive response of naive T cells is enhanced by IREM-2 activation of mDCs.
Additional information: Clone REA1070 displays negligible binding to Fc receptors.

Alternative names

CD300LE, CLM-2, CMRF35-A5, IREM-2, PIgR-2, LMIR6

Technical specifications

  • Antigen: CD300e (IREM-2)
  • Clone: REA1070
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CD300LE, CLM-2, CMRF35-A5, IREM-2, PIgR-2, LMIR6
  • Entrez Gene ID: 342510
  • Molecular mass of antigen [kDa]: 21
  • Distribution of antigen: dendritic cells, monocytes
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates:
Product options: 1
100 µg in 100 µL
CAD 245.00