CD273 (PD-L2) antibodies, human

CD273 (PD-L2) antibodies, human

Clone: REA985
Clone REA985 recognizes the human CD273 antigen, also known as B7-DC or PD-L2. CD273 with an approximate molecular weight of 29 kDa is a type I transmembrane protein, belonging to the B7 family of protein ligands and to the Ig superfamily. CD273 is mainly expressed on dendritic cells (DCs) and activated macrophages. It has been shown to interact with programmed-death-receptor 1 (PD-1). A stimulatory as well as a inhibitory role of CD273 in T cell activation has been proposed.
Additional information: Clone REA985 displays negligible binding to Fc receptors.

Alternative names

PDCD1LG2, B7-DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2

Technical specifications

  • Antigen: CD273 (PD-L2)
  • Clone: REA985
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: PDCD1LG2, B7-DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2
  • Entrez Gene ID: 80380
  • Molecular mass of antigen [kDa]: 29
  • Distribution of antigen: dendritic cells, macrophages
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates:
Product options: 1
100 µg in 100 µL
CAD 245.00