CD218 (IL-18Rα) antibodies, human

CD218 (IL-18Rα) antibodies, human

Clone: H44 | Dilution: 1:11
Clone H44 recognizes the CD218 antigen, which is also known as interleukin-18 receptor α chain (IL-18Rα) receptor, is an heterodimeric receptor complex and composed of the IL-18Rα chain and the IL-1 receptor accessory protein-like (IL-1RacPL) or IL-18Rβ chain. CD218 represents the ligand-binding chain, whereas IL-18Rβ is suggested to assist in the formation of a high affinity complex and mediates intracellular signals. IL-18R is expressed on a variety of cells including macrophages, neutrophils, natural killer (NK) cells, endothelial, and smooth muscle cells and an upregulated expression is observed on naive T cells, T helper cell type 1 (Tʜ1) cells, and B cells, in the presence of IL-12.

Alternative names

IL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP

Technical specifications

  • Antigen: CD218 (IL-18Rα)
  • Clone: H44
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: IL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP
  • Distribution of antigen: NK cells, endothelial cells, macrophages, neutrophils
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Kim, S. H. et al. (2001) Functional reconstitution and regulation of IL-18 activity by the IL-18Rβ chain. J. Immunol. 166: 148-154
    2. Nakamura, S. et al. (2000) Expression and responsiveness of human interleukin-18 receptor (IL-18R) on hematopoietic cell lines. Leukemia 14(6): 1052-1059
Product options: 9
for 30
tests
(1)
CAD 105.00
for 30
tests
(1)
CAD 105.00
for 100
tests
(1)
CAD 315.00
for 30
tests
(1)
CAD 105.00
for 100
tests
(1)
CAD 315.00
for 30
tests
(1)
CAD 105.00
for 100
tests
(1)
CAD 320.00
for 30
tests
(1)
CAD 110.00
for 100
tests
(1)
CAD 315.00

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