Anti-TCR Vβ5.3 antibodies, human

Anti-TCR Vβ5.3 antibodies, human

Clone: REA670 | Dilution: 1:11
Clone REA670 recognizes the human variable beta 5.3 subunit of the α/β T cell receptor (TCR Vβ5.3), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.3 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. TCR Vβ5.3 is expressed on a subset of peripheral blood T cells.
Additional information: Clone REA670 displays negligible binding to Fc receptors.

Alternative names

TCR Vbeta5.3, TCR Vb5.3

Technical specifications

  • Antigen: TCR Vβ5.3
  • Clone: REA670
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCR Vbeta5.3, TCR Vb5.3
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, Biotin
  • Selected references

    1. Born, W. et al. (1985) Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc. Natl. Acad. Sci. U.S.A. 82(9): 2925-2929
    2. Adari, H. et al. (1995)
      Expression of the human T-cell receptor V beta 5.3 in
      Escherichia coli
      by thermal induction of the trc promoter: nucleotide sequence of the lacIts gene.
      DNA Cell Biol. 14(11): 945-950
    3. Bleux, C. et al. (1995) A mouse monoclonal antibody specific for the V beta 5.3 chain of the human TcR recognizes a subgroup of the mouse TcR V beta 8.2 chains. J. Leukoc. Biol. 57(3): 491-491
Product options: 8
for 30
tests
(1)
CAD 190.00
for 100
tests
(1)
CAD 470.00
for 30
tests
(1)
CAD 130.00
for 100
tests
(1)
CAD 370.00
for 30
tests
(1)
CAD 170.00
for 100
tests
(1)
CAD 390.00
for 30
tests
(1)
CAD 105.00
for 100
tests
(1)
CAD 315.00

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