Anti-IL-1α antibodies, human

Anti-IL-1α antibodies, human

Clone: 364-3B3-14 | Dilution: 1:10
Clone 364-3B3-14 recognizes the human IL-1α antigen, a cytokine of the interleukin-1 (IL-1) family. IL-1α is produced mainly by activated macrophages, neutrophils, as well as epithelial and endothelial cells. IL-1 is responsible for the production of inflammation as well as the promotion of fever and sepsis. IL-1α interacts with TNF and promote fever and inflammation. The 364-3B3-14 antibody does not cross-react with human IL-1β.

Alternative names

IL-1 alpha, H-1, LAF, BAF, OAF, PIF

Technical specifications

  • Antigen: IL-1α
  • Clone: 364-3B3-14
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: IL-1 alpha, H-1, LAF, BAF, OAF, PIF
  • Entrez Gene ID: 3552
  • Molecular mass of antigen [kDa]: 18
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: macrophages, epithelial cells, neutrophils, endothelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
  • Selected references

    1. March, C. J. et al. (1985) Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs. Nature 315(6021): 641-647
    2. Nicklin, M. J. et al. (1994) A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes. Genomics 19(2): 382-384
    3. Satoh, H. et al. (1994) Characterization of anti-IL-1α autoantibodies in the sera from healthy humans. Immunopharmacology 27(2): 107-118
Product options: 4
for 30
tests
(1)
CAD 130.00
for 100
tests
(1)
CAD 370.00
for 30
tests
(1)
CAD 165.00
for 100
tests
(1)
CAD 385.00

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