Clone:
REA1198
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC

Extended validation for H-2Kb Antibody, anti-mouse, REAfinity™

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with REA1198
AF6-88.5++
Cells were incubated with an excess of purified unconjugated H-2Kb (REA1198) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for H-2Kb Antibody, anti-mouse, REAfinity™

Overview

Clone REA1198 recognizes the mouse H-2Kb MHC class I alloantigen expressed on mouse MHC class I–positive cells of the H-2Kb haplotype. H-2K is a polymorphic cell-surface glycoprotein which plays a role in the presentation of foreign antigens to the immune system. Clone REA1198 does not cross-react with the d, f, j, k, p, q, r, s, u and v haplotypes.
Additional information: Clone REA1198 displays negligible binding to Fc receptors.

Detailed product information

Technical specifications

CloneREA1198
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenH-2Kb
Entrez Gene ID14964
RRIDAB_2801956, AB_2801957, AB_2801958, AB_2801959, AB_2801960, AB_2801961, AB_2801955

Resources for H-2Kb Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for H-2Kb Antibody, anti-mouse, REAfinity™

Publications

  1. York, I. A. et al. (1996) Antigen processing and presentation by the class I major histocompatibility complex. Annu. Rev. Immunol. 14: 369-396

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