Clone:
REAL1291
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
PHF-tau, Mapt, Mtapt

Specifications for Tau Antibody, anti-human, REAdye_lease™

Overview

Clone REAL1291 is an antibody fragment derived from the full Tau antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL1291 recognizes the antigen Tau, a protein expressed in neurons. Tau belongs to the family of microtubule-associated proteins (MAPs), whose members interact with the microtubules of the cellular cytoskeleton and have different functions. The binding of MAPs to tubulin dimers of microtubules leads to the stabilization of microtubule structure.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

PHF-tau, Mapt, Mtapt

Detailed product information

Technical specifications

CloneREAL1291
Clonalitymonoclonal
Isotype controlControl Antibody
Hosthuman cell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenTau
Alternative names of antigenPHF-tau, Mapt, Mtapt
Distribution of antigenneurons

Resources for Tau Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for Tau Antibody, anti-human, REAdye_lease™

Publications

  1. Lee, G. et al. (1989) The microtubule binding domain of tau protein. Neuron 2(6): 1615-1624
  2. Yoshida, H. et al. (2012) Phosphorylation of microtubule-associated protein tau by AMPK-related kinases. J. Neurochem. 120(1): 165-176
  3. Wang, Y. et al. (2016) Tau in physiology and pathology. Nat. Rev. Neurosci. 17(1): 5-21

Related products for
Tau Antibody, anti-human, REAdye_lease™

1 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?