PepTivator® PSA, human

PepTivator
®
PSA is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the sequence of human prostate specific antigen PSA (UniProt ID: P07288).
In vitro
stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells.

Specifications for
PepTivator
®
PSA
, human

Overview

PepTivator
®
PSA is a pool of lyophilized peptides, consisting mainly of 15-mer sequences with 11 amino acids overlap, covering the sequence of human prostate specific antigen PSA (UniProt ID: P07288).
In vitro
stimulation of antigen-specific T cells with PepTivator Peptide Pools causes the secretion of effector cytokines and the up-regulation of activation markers, which then allow the detection and isolation of antigen-specific T cells.

Detailed product information

Background information

The 261 amino acid prostate-specific antigen (PSA) is highly expressed in prostate tumors and a potential target for immunotherapeutic approaches in prostate cancer.

Applications

PepTivator PSA – research grade has been specifically developed for efficient
in vitro
stimulation of PSA–specific T cells. Peptides of 15 amino acids in length and 11 amino acids overlap represent an optimized solution for stimulating both CD4
+
and CD8
+
T cells in various applications, including:
  • Detection and analysis of PSA–specific effector/memory T cells in PBMCs by MACS® Cytokine Secretion Assays, intracellular cytokine staining, or other technologies.
  • Isolation of viable PSA–specific CD4+ T cells with the CD154 MicroBead Kit, or of CD4+ and CD8+ T cells using the CD137 MicroBead Kit or MACS Cytokine Secretion Assay – Cell Enrichment and Detection Kits. Subsequently, cells can be expanded for generation of T cell lines.
  • Generation of PSA–specific effector/memory T cells from naive T cell populations.
  • Pulsing of antigen-presenting cells.

Related products for
PepTivator
®
PSA
, human

3 products available
 

Rapid Cytokine Inspector (CD4/CD8 T Cell) Kit, human

T lymphocytes execute and control immunological reactions with a repertoire of cytokines, cytotoxic ...

 

CD137 MicroBead Kit, human

The CD137 MicroBead Kit was developed for the positive selection of human CD137+ cells from PBMCs. ...

 

CD154 MicroBead Kit, human

The CD154 MicroBead Kit has been developed for positive selection of activated CD154+ ...

Seems like you are coming from USA!
Do you want to visit our website in your country?

Copyright © 2023 Miltenyi Biotec and/or its affiliates. All rights reserved.