Clone:
REAL1317
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
MUC-2, MUC2, SMUC, Intestinal mucin-2

Specifications for Mucin-2 Antibody, anti-human, REAdye_lease™

Overview

Clone REAL1317 is an antibody fragment derived from the full Mucin-2 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL1317 recognizes human Mucin-2, also known as MUC2, is an oligomeric mucus gel-forming glycoprotein secreted onto mucosal surfaces. It belongs to the mucin protein family, polymerizes into a gel and provides an insoluble mucous barrier that serves to protect the intestinal epithelium. Mucins may show aberrant expression, localization, and/or glycosylation in multiple malignancies.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

MUC-2, MUC2, SMUC, Intestinal mucin-2

Detailed product information

Technical specifications

CloneREAL1317
Clonalitymonoclonal
Isotype controlControl Antibody
Hosthuman cell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenMucin-2
Alternative names of antigenMUC-2, MUC2, SMUC, Intestinal mucin-2

Resources for Mucin-2 Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
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to search for Certificates of Analysis (CoA) by lot number.

References for Mucin-2 Antibody, anti-human, REAdye_lease™

Publications

  1. Pinto, R. et al. (2012) Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation. J. Cell. Mol. Med. 16(7): 1474-1484
  2. Yamashita, M. S. A. et al. (2018) Mucin 2 (MUC2) promoter characterization: an overview. Cell Tissue Res. 374(3): 455-463
  3. Astashchanka, A. et al. (2019) Mucin 2 (MUC2) modulates the aggressiveness of breast cancer. Genetics 173(2): 289-299

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