IL-17 Secretion Assay – Detection Kits, human

IL-17 Secretion Assay – Detection Kits, human

The IL-17 Secretion Assay was developed for the detection of viable human IL-17–secreting leukocytes from PBMCs.

Background information

IL-17 is produced by CD4
+
T helper cells, a T cell subset termed Th17, which also secrete IL-17F and IL-22 and express the NK cell marker CD161
1
. IL-17 secretion has also been described for other cell types, such as CD8
+
memory T cells.
Th17 cells are involved in the recruitment of neutrophils to control early stages of infections by a number of pathogens, such as extracellular bacteria and fungi. IL-17 and Th17 cells play an important role in immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriasis, multiple sclerosis, asthma, and inflammatory bowel disease.
  • Selected References

    1. Cosmi, L. et al. (2008)
      Human interleukin 17–producing cells originate from a CD161
      +
      CD4
      +
      T cell precursor.
      J. Exp. Med. 205: 1903-1916
Product options: 2
130-094-536

IL-17 Secretion Assay – Detection Kit (APC), human

for 100
tests
(1)
EUR 680,00 
130-094-537

IL-17 Secretion Assay – Detection Kit (PE), human

for 100
tests
(1)
EUR 592,00