REAlease® CD54 (ICAM-1) Complexes, mouse

REAlease
®
CD54 (ICAM-1) Complexes
, mouse

Clone: REAL289 | Dilution: 1:50
Clone REAL289 is an antibody fragment derived from the full CD54 (ICAM-1) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL289 recognizes the murine CD54 antigen, a type I transmembrane glycoprotein also known as intercellular adhesion molecule 1 (ICAM-1). CD54 is continuously present in low concentrations in the membranes of monocytes/macrophages, lymphocytes, activated endothelial cells, granulocytes, and dendritic cells. Its expression is regulated by inflammatory cytokines and can be induced by interleukin 1 (IL-1) and tumor necrosis factor. CD54 is a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). When activated, leukocytes bind to endothelial cells via CD54/LFA-1 and then transmigrate into tissues.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative Names

ICAM-1, Ly-47, MALA-2

Technical specifications

  • Antigen: CD54 (ICAM-1)
  • Clone: REAL289
  • Isotype control: REAL Control
  • Alternative names of antigen: ICAM-1, Ly-47, MALA-2
  • Distribution of antigen: monocytes, macrophages, lymphocytes, endothelial cells, granulocytes, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC
Product options: 1

Product information

Size
Order no.
Price

REAlease CD54 (ICAM-1)-APC, mouse

  • REAL289
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-115-986
EUR 105,00 

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