CD8a antibodies, mouse

CD8a antibodies, mouse

Clone: REA601 | Dilution: 1:50
Clone REA601 is specific for the mouse CD8a antigen, also known as LY-2 or T8, which is expressed on cytotoxic T cells and at lower levels on subpopulations of dendritic cells and TCRγ/δ
+
cells. CD8a is further detected on most thymocytes (CD4
+
CD8a
+
and CD4
CD8
+
thymocytes). Cytotoxic T cells and thymocytes express CD8a as heterodimer with CD8b, whereas dendritic cells and TCRγ/δ
+
cells express a CD8a/CD8a homodimer. It mediates efficient cell-cell interactions within the immune system.
Additional information: Clone REA601 displays negligible binding to Fc receptors.

Alternative Names

CD8, Leu-2, Ly-2, T8, Lyt-2

Technical specifications

  • Antigen: CD8a
  • Clone: REA601
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CD8, Leu-2, Ly-2, T8, Lyt-2
  • Entrez Gene ID: 12525
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: dendritic cells, NK cells, red blood cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, PE-Vio770, APC-Vio770
REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 
Other clonesOverlap in epitope recognition with REA601
53-6.7++
Product options: 6

Product information

Size
Order no.
Price

CD8a-APC, mouse

  • REA601
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-776
EUR 83,00 

CD8a-APC, mouse

  • REA601
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-664
EUR 259,00 

CD8a-PE-Vio770, mouse

  • REA601
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-119-123
EUR 136,00 

CD8a-PE-Vio770, mouse

  • REA601
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-118-946
EUR 252,00 

CD8a-APC-Vio770, mouse

  • REA601
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-120-806
EUR 100,00 

CD8a-APC-Vio770, mouse

  • REA601
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-120-737
EUR 280,00 

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