CD89 antibodies, human

CD89 antibodies, human

Clone: REA234 | Dilution: 1:11
Clone REA234 recognizes CD89, the human myeloid IgA Fc receptor. CD89 is a glycosylated transmembrane protein that binds both IgA subclasses (IgA1 and IgA2) and is closely related to the KIR and MIR proteins rather than to other human Fc receptors. CD89 itself lacks the canonical signal transduction domains, however it associates with the FcR γ-chain with an immunoreceptor tyrosine-based activation (ITAM) motif, which allows transduction of activation signal upon ligand binding. FcαRI alone mediates endocytosis and recyling of IgA. Expression of CD89 is found on neutrophils, eosinophils, monocytes/macrophages, dendritic cells, and Kupffer cells.
Additional information: Clone REA234 displays negligible binding to Fc receptors.

Alternative Names

FCAR

Technical specifications

  • Antigen: CD89
  • Clone: REA234
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FCAR
  • Distribution of antigen: monocytes, macrophages, dendritic cells, eosinophils, neutrophils
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD89-FITC, human

  • REA234
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-387
EUR 74,00 

CD89-FITC, human

  • REA234
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-385
EUR 185,00 

CD89-PE, human

  • REA234
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-388
EUR 91,00 

CD89-PE, human

  • REA234
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-386
EUR 236,00 

CD89-APC, human

  • REA234
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-384
EUR 113,00 

CD89-APC, human

  • REA234
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-383
EUR 255,00 

CD89-PE-Vio770, human

  • REA234
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-369
EUR 113,00 

CD89-PE-Vio770, human

  • REA234
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-366
EUR 278,00 

CD89-APC-Vio770, human

  • REA234
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-364
EUR 101,00 

CD89-APC-Vio770, human

  • REA234
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-361
EUR 278,00 

CD89-Biotin, human

  • REA234
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-373
EUR 74,00 

CD89-Biotin, human

  • REA234
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-370
EUR 236,00 

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