CD85a (ILT5) antibodies, human

CD85a (ILT5) antibodies, human

Clone: REA207 | Dilution: 1:11
Clone REA207 recognizes the CD85a antigen, a immunoglobulin superfamily transmembrane glycoprotein also known as leukocyte immunoglobulin-like receptor member 3 (LIR-3) or immunoglobulin-like transcript 5 (ILT5). CD85a is preferentially expressed by monocytes, macrophages, dendritic cells, and granulocytes. It provides inhibitory signals through interaction with MHC class I molecules and becomes activated upon co-ligation of CD85a and immune receptors, such as CD32 and the B cell receptor. CD85a down-regulates antigen-induced B cell–activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitory motifs.
Additional information: Clone REA207 displays negligible binding to Fc receptors.

Alternative names

LILRB3, HL9, ILT5, LILRA6, LIR-3, PIRB

Technical specifications

  • Antigen: CD85a (ILT5)
  • Clone: REA207
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LILRB3, HL9, ILT5, LILRA6, LIR-3, PIRB
  • Distribution of antigen: macrophages, granulocytes, dendritic cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Borges, L. et al. (1997) A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J. Immunol. 159: 5192-5196
    2. Ma, G. et al. (2011) Paired immunoglobin-like receptor-B regulates the suppressive function and fate of myeloid-derived suppressor cells. Immunity 34(3): 385-395
    3. Colonna, M. et al. (1999) Inhibitory and activating receptors involved in immune surveillance by human NK and myeloid cells. J. Leukoc. Biol. 66: 718-722
Product options: 14
for 30
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(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
for 30
tests
(1)
EUR 110,00 
for 100
tests
(1)
EUR 265,00 
for 30
tests
(1)
EUR 110,00 
for 100
tests
(1)
EUR 265,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 275,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 

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