CD79b antibodies, mouse

CD79b antibodies, mouse

Clone: REA1117 | Dilution: 1:50
Clone REA1117 recognizes the mouse CD79b antigen, a 35–40kD single-pass type I membrane protein also known as B cell antigen receptor complex-associated protein beta chain (Igβ chain). The heterodimeric CD79 molecule is composed of an α chain (CD79a) and a β chain (CD79b) and is associated with surface immunoglobulins to form the B cell receptor. The CD79a/CD79b heterodimer facilitates the differentiation of pre–B cells from pro–B cells, surface expression of surface Ig, signal transduction following antigen recognition, and endocytosis of recognized antigens. Crosslinking of CD79b
in vitro
by monoclonal antibodies activates pre–B cells but blocks terminal differentiation of all plasma cell isotypes. It was shown that a combination of CD79a and CD79b monoclonal antibodies can effectively deplete B cells from peripheral blood, spleen, bone marrow, and lymph nodes in mice.
Additional information: Clone REA1117 displays negligible binding to Fc receptors.

Alternative Names

Ig-beta, B29, Igb

Technical specifications

  • Antigen: CD79b
  • Clone: REA1117
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Ig-beta, B29, Igb
  • Entrez Gene ID: 15985
  • Molecular mass of antigen [kDa]: 23
  • Distribution of antigen: B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770
Product options: 6

Product information

Size
Order no.
Price

CD79b-PE, mouse

  • REA1117
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-119-425
EUR 59,00 

CD79b-PE, mouse

  • REA1117
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-119-325
EUR 207,00 

CD79b-APC, mouse

  • REA1117
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-119-426
EUR 85,00 

CD79b-APC, mouse

  • REA1117
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-119-326
EUR 238,00 

CD79b-PE-Vio770, mouse

  • REA1117
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-119-428
EUR 104,00 

CD79b-APC-Vio770, mouse

  • REA1117
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-119-429
EUR 111,00