CD72 antibodies, human

CD72 antibodies, human

Clone: REA231 | Dilution: 1:11
Clone REA231 recognizes CD72, a 45 kDa type II membrane protein with a C-type lectin-like domain. Expression of CD72 is found on most B-lineage cells, follicular dendritic cells, mast cells, and liver Kupffer cells. CD72 is recognized as negative regulator of B cell receptor (BCR) signaling, as well as regulating mast cell growth and differentiation via KIT activation. The inhibitory role of CD72 is exerted via the ITIM sequence in the cytoplasmic tail.
Additional information: Clone REA231 displays negligible binding to Fc receptors.

Alternative Names

CD72b, Lyb-2

Technical specifications

  • Antigen: CD72
  • Clone: REA231
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CD72b, Lyb-2
  • Distribution of antigen: B cells, mast cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin
  • Selected References

    1. Kataoka, T. R. et al. (2010) CD72 negatively regulates KIT-mediated responses in human mast cells. J. Immunol. 184: 2468-2475
    2. Li, D. H. et al. (2006) CD72 down-modulates BCR-induced signal transduction and diminishes survival in primary mature B lymphocytes. J. Immunol. 176: 5321-5328
Product options: 14

Product information

Size
Order no.
Price

CD72-FITC, human

  • REA231
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-340
EUR 90,00 

CD72-FITC, human

  • REA231
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-338
EUR 220,00 

CD72-PE, human

  • REA231
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-336
EUR 110,00 

CD72-PE, human

  • REA231
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-335
EUR 265,00 

CD72-APC, human

  • REA231
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-334
EUR 110,00 

CD72-APC, human

  • REA231
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-333
EUR 265,00 

CD72-VioBlue, human

  • REA231
  • 1:11
  • For research use only
for 30
tests
(1)
130-106-502
EUR 115,00 

CD72-VioBlue, human

  • REA231
  • 1:11
  • For research use only
for 100
tests
(1)
130-106-454
EUR 275,00 

CD72-PE-Vio770, human

  • REA231
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-330
EUR 120,00 

CD72-PE-Vio770, human

  • REA231
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-327
EUR 290,00 

CD72-APC-Vio770, human

  • REA231
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-325
EUR 120,00 

CD72-APC-Vio770, human

  • REA231
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-321
EUR 290,00 

CD72-Biotin, human

  • REA231
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-332
EUR 90,00 

CD72-Biotin, human

  • REA231
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-331
EUR 220,00