CD62L antibodies, human

CD62L antibodies, human

Clone: 145/15 | Dilution: 1:11
Clone 145/15 recognizes the human CD62L antigen, a 74 kDa glycoprotein and a member of the selectin family of cell surface molecules. CD62L is also known as L-selectin, LECAM-1, or LAM-1 and binds a series of glycoproteins including CD34, GlyCAM-1, and MAdCAM-1. CD62L is important for homing of naive lymphocytes via endothelial venules to peripheral lymph nodes and Peyer’s patches. The CD62L antigen also contributes to the recruitment of leukocytes from the blood to areas of inflammation. Most hematopoietic cells express CD62L, including many peripheral blood B cells, T cells, monocytes, granulocytes, and some myeloid cells from bone marrow, and thymocytes. CD62L is continuously endoproteolytically cleaved from the cell surface neutrophils and lymphocytes (shedding). Proteolysis is accelerated, for example, after antigenic activation of T cells.
Always use fresh material for immunofluorescent staining of CD62L
cells. For optimal results, the cells should not be older than 8–12 hours. Keep cells continuously cold. CD62L-expression may be rapidly lost due to shedding.

Alternative Names

Sell, LAM1, LECAM1, LEU8, Lnhr, LSEL, Lyam1, PLNHR, TQ1, LAM-1

Technical specifications

  • Antigen: CD62L
  • Clone: 145/15
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Sell, LAM1, LECAM1, LEU8, Lnhr, LSEL, Lyam1, PLNHR, TQ1, LAM-1
  • Entrez Gene ID: 6402
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: B cells, bone marrow, eosinophils, granulocytes, Langerhans cells, lymphocytes, monocytes, neutrophils, NK cells, red blood cells, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, Biotin
Product options: 2

Product information

Order no.

CD62L-Biotin, human

  • 145/15
  • 1:11
  • For research use only
for 30
EUR 90,00 

CD62L-Biotin, human

  • 145/15
  • 1:11
  • For research use only
for 100
EUR 220,00 

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