CD59a antibodies, mouse

CD59a antibodies, mouse

Clone: REA287 | Dilution: 1:10
Clone REA287 recognizes the CD59a antigen, the murine analog of human CD59 which is also known as MAC-inhibitory protein (MAC-IP) or membrane attack complex inhibition factor (MACIF). CD59a is widely distributed, being present on all circulating cells, epithelia, and endothelia and in most tissues examined. CD59a blocks the formation of the membrane attack complex of complement by inhibiting binding of C9 to the C5b-8 complex, hereby protecting the cells from complement-mediated lysis. Further, CD59a down-modulates CD4
+
T cell activity
in vitro
and
in vivo
, thereby revealing another link between complement regulators and T cell activation.
Additional information: Clone REA287 displays negligible binding to Fc receptors.

Alternative Names

MAC-inhibitory protein (MAC-IP), Membrane attack complex inhibition factor (MACIF), Protectin, CD59

Technical specifications

  • Antigen: CD59a
  • Clone: REA287
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: MAC-inhibitory protein (MAC-IP), Membrane attack complex inhibition factor (MACIF), Protectin, CD59
  • Entrez Gene ID: 12509
  • Molecular mass of antigen [kDa]: 8
  • Distribution of antigen: leukocytes, epithelial cells, endothelial cells, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD59a-PE, mouse

  • REA287
  • 1:10
  • For research use only
9 µg in 300 µL
130-104-143
EUR 27,00 

CD59a-PE, mouse

  • REA287
  • 1:10
  • For research use only
30 µg in 1 mL
130-104-105
EUR 54,00 

CD59a-APC, mouse

  • REA287
  • 1:10
  • For research use only
9 µg in 300 µL
130-104-142
EUR 44,00 

CD59a-APC, mouse

  • REA287
  • 1:10
  • For research use only
30 µg in 1 mL
130-104-104
EUR 86,00 

CD59a-PE-Vio770, mouse

  • REA287
  • 1:10
  • For research use only
9 µg in 300 µL
130-104-144
EUR 44,00 

CD59a-PE-Vio770, mouse

  • REA287
  • 1:10
  • For research use only
30 µg in 1 mL
130-104-106
EUR 86,00 

CD59a-Biotin, mouse

  • REA287
  • 1:10
  • For research use only
9 µg in 300 µL
130-104-141
EUR 15,00 

CD59a-Biotin, mouse

  • REA287
  • 1:10
  • For research use only
30 µg in 1 mL
130-104-103
EUR 32,00 

Related products

3 products available