CD55 (DAF) antibodies, human

CD55 (DAF) antibodies, human

Clone: JS11 | Dilution: 1:11
Clone JS11 recognizes the CD55 antigen, a 70 kDa glycosylphosphatidylinositol-anchored single chain glycoprotein, which is also known as complement decay-accelerating factor (DAF). CD55 is broadly distributed among hematopoietic and non-hematopoietic cells. It is expressed on the plasma membranes of all cell types that are in intimate contact with serum and on the surfaces of epithelial cells lining the extracellular compartments. Variants of the molecule are present in body fluids and in extracellular matrix. CD55 plays multiple physiologic roles including tissue protection from the cytotoxic complement injury, anti-inflammatory function owing to its anti-adherence properties which enhance transmigration of monocytes and macrophages and reduce tissue injury. CD55 plays an essential role during pregnancy and is involved in the protection of the semiallogeneic fetus and in preventing uncontrolled infiltration by white cells. It is exploited in multiple pathologic conditions by pathogens and viruses in chronic tissue infection processes.

Alternative Names

CR, CROM, DAF, TC

Technical specifications

  • Antigen: CD55 (DAF)
  • Clone: JS11
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CR, CROM, DAF, TC
  • Distribution of antigen: B cells, T cells, monocytes, NK cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected References

    1. Caras, I. W. et al. (1987) Cloning of decay-accelerating factor suggests novel use of splicing to generate two proteins. Nature 325(6104): 545-549
    2. Nowicki, B. et al. (2013) DAF as a therapeutic target for steroid hormones: implications for host-pathogen interactions. Adv. Exp. Med. Biol. 734: 83-96
    3. Osuka, F. et al. (2006) Molecular cloning and characterization of novel splicing variants of human decay-accelerating factor. Genomics 88(3): 316-322
Product options: 12

Product information

Size
Order no.
Price

CD55 (DAF)-FITC, human

  • JS11
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-804
EUR 74,00 

CD55 (DAF)-FITC, human

  • JS11
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-765
EUR 185,00 

CD55 (DAF)-PE, human

  • JS11
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-805
EUR 91,00 

CD55 (DAF)-PE, human

  • JS11
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-764
EUR 236,00 

CD55 (DAF)-APC, human

  • JS11
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-802
EUR 113,00 

CD55 (DAF)-APC, human

  • JS11
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-768
EUR 255,00 

CD55 (DAF)-PE-Vio770, human

  • JS11
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-806
EUR 113,00 

CD55 (DAF)-PE-Vio770, human

  • JS11
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-783
EUR 278,00 

CD55 (DAF)-APC-Vio770, human

  • JS11
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-803
EUR 101,00 

CD55 (DAF)-APC-Vio770, human

  • JS11
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-767
EUR 278,00 

CD55 (DAF)-Biotin, human

  • JS11
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-815
EUR 74,00 

CD55 (DAF)-Biotin, human

  • JS11
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-818
EUR 236,00