CD55 (DAF) antibodies, human

CD55 (DAF) antibodies, human

Clone: JS11 | Dilution: 1:11
Clone JS11 recognizes the CD55 antigen, a 70 kDa glycosylphosphatidylinositol-anchored single chain glycoprotein, which is also known as complement decay-accelerating factor (DAF). CD55 is broadly distributed among hematopoietic and non-hematopoietic cells. It is expressed on the plasma membranes of all cell types that are in intimate contact with serum and on the surfaces of epithelial cells lining the extracellular compartments. Variants of the molecule are present in body fluids and in extracellular matrix. CD55 plays multiple physiologic roles including tissue protection from the cytotoxic complement injury, anti-inflammatory function owing to its anti-adherence properties which enhance transmigration of monocytes and macrophages and reduce tissue injury. CD55 plays an essential role during pregnancy and is involved in the protection of the semiallogeneic fetus and in preventing uncontrolled infiltration by white cells. It is exploited in multiple pathologic conditions by pathogens and viruses in chronic tissue infection processes.

Alternative names

CR, CROM, DAF, TC

Technical specifications

  • Antigen: CD55 (DAF)
  • Clone: JS11
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CR, CROM, DAF, TC
  • Distribution of antigen: B cells, T cells, monocytes, NK cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Caras, I. W. et al. (1987) Cloning of decay-accelerating factor suggests novel use of splicing to generate two proteins. Nature 325(6104): 545-549
    2. Nowicki, B. et al. (2013) DAF as a therapeutic target for steroid hormones: implications for host-pathogen interactions. Adv. Exp. Med. Biol. 734: 83-96
    3. Osuka, F. et al. (2006) Molecular cloning and characterization of novel splicing variants of human decay-accelerating factor. Genomics 88(3): 316-322
Product options: 12
130-101-804

CD55 (DAF)-FITC, human

for 30
tests
(1)
EUR 90,00 
130-101-765

CD55 (DAF)-FITC, human

for 100
tests
(1)
EUR 220,00 
130-101-805

CD55 (DAF)-PE, human

for 30
tests
(1)
EUR 110,00 
130-101-764

CD55 (DAF)-PE, human

for 100
tests
(1)
EUR 265,00 
130-101-802

CD55 (DAF)-APC, human

for 30
tests
(1)
EUR 110,00 
130-101-768

CD55 (DAF)-APC, human

for 100
tests
(1)
EUR 265,00 
130-101-806

CD55 (DAF)-PE-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-101-783

CD55 (DAF)-PE-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-101-803

CD55 (DAF)-APC-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-101-767

CD55 (DAF)-APC-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-101-815

CD55 (DAF)-Biotin, human

for 30
tests
(1)
EUR 90,00 
130-101-818

CD55 (DAF)-Biotin, human

for 100
tests
(1)
EUR 220,00