CD49d antibodies, mouse

CD49d antibodies, mouse

Clone: REA807 | Dilution: 1:50
Clone REA807 recognizes the mouse CD49d antigen, a 150 kDa integrin family member, also known as integrin α4 chain. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cell-matrix interaction. CD49d associates non-covalently with the integrin ß or ß1 (CD29) forming the complex VLA4, which is expressed on peripheral lymphocytes, thymocytes, eosinophils, basophils, mast cells, dendritic cells, and monocytes. VLA4 plays a critical role in adhesion and migration of cells into tissues by binding to its ligand VCAM-1 (CD106). Together with the ß7 integrin, CD49d forms the heterodimer LPAM-1, which is a ligand for the mucosal vascular addressin (MAdCAM-1).
Additional information: Clone REA807 displays negligible binding to Fc receptors.

Alternative Names

ITGA4, Itga4B, VLA-4α, Integrin alpha-4

Technical specifications

  • Antigen: CD49d
  • Clone: REA807
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: ITGA4, Itga4B, VLA-4α, Integrin alpha-4
  • Entrez Gene ID: 16401
  • Molecular mass of antigen [kDa]: 111
  • Distribution of antigen: B cells, basophils, cardiac muscle, dendritic cells, eosinophils, Langerhans cells, lymphocytes, macrophages, mast cells, monocytes, myeloid cells, NK cells, placenta, red blood cells, skeletal muscle, smooth muscle, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD49d-PE, mouse

  • REA807
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-977
EUR 57,00 

CD49d-PE, mouse

  • REA807
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-824
EUR 224,00 

CD49d-APC, mouse

  • REA807
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-978
EUR 83,00 

CD49d-APC, mouse

  • REA807
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-825
EUR 259,00 

CD49d-PE-Vio770, mouse

  • REA807
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-979
EUR 101,00 

CD49d-PE-Vio770, mouse

  • REA807
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-826
EUR 274,00 

CD49d-Biotin, mouse

  • REA807
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-111-976
EUR 32,00 

CD49d-Biotin, mouse

  • REA807
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-111-823
EUR 147,00 

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