CD49d antibodies, human

CD49d antibodies, human

Clone: MZ18-24A9 | Dilution: 1:11
CD49d, also known as the α4 integrin chain or VLA-4α chain, is a 150 kDa cell adhesion protein that is directly involved in mononuclear leukocyte trafficking. Dimerized with β7 integrin, the resulting α4β7 integrin binds VCAM-1 (CD106), MAdCAM-1, and fibronectin to facilitate the rolling of leukocytes along vascular epithelium. In T cells, on ligation of MAdCAM-1, α4β7 integrin also provides costimulation of T cell receptor/CD3–mediated signaling.
CD49d is expressed on most mononuclear leukocytes, both in circulation or in lymphoid or other tissues, as well as on eosinophils and basophils.

Alternative names

ITGA4, IA4, VLA-4α

Technical specifications

  • Antigen: CD49d
  • Clone: MZ18-24A9
  • Isotype: mouse IgG2bκ
  • Isotype control: Mouse IgG2b – isotype control antibodies
  • Alternative names of antigen: ITGA4, IA4, VLA-4α
  • Entrez Gene ID: 3676
  • Molecular mass of antigen [kDa]: 111
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
  • Distribution of antigen: B cells, basophils, cardiac muscle, dendritic cells, eosinophils, Langerhans cells, lymphocytes, macrophages, mast cells, monocytes, myeloid cells, NK cells, placenta, red blood cells, skeletal muscle, smooth muscle, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE-Vio770, Biotin, pure, PE, FITC
Product options: 7
130-099-691

CD49d-PE, human

for 30
tests
(1)
EUR 110,00 
130-093-282

CD49d-PE, human

for 100
tests
(1)
EUR 265,00 
for 30
tests
(1)
EUR 120,00 
for 100
tests
(1)
EUR 290,00 
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
100 µg in 1 mL
EUR 156,00