CD44v6 antibodies, human

CD44v6 antibodies, human

Clone: REA706 | Dilution: 1:50
Clone REA706 recognizes the CD44v6 antigen. CD44 is the receptor for hyaluronic acid (HA), which plays an important role in cell migration, tumor growth, and progression. CD44 is involved in the modification of the activity of receptors including MET and the ERBB family of tyrosine kinases. CD44 is a marker for many types of cancer stem cells (CSC), including breast CSCs that possess higher tumorigenicity and metastatic potential, colorectal, pancreatic, and prostate CSCs. In addition, expression was observed in several cancers as well as on carcinoma cell lines. Here, CD44 plays a role in cancer cell migration and matrix adhesion in response to a cellular microenvironment, thus enhancing cellular aggregation and tumor cell growth. CD44 is also expressed on mesodermal cells, such as hematopoietic, fibroblastic, and glial cells.
Additional information: Clone REA706 displays negligible binding to Fc receptors.

Alternative Names

CDw44, Epican, ECMR-III, PGP-I, CSPG9, EMCR III, HCELL, HUTCH-I, H-CAM

Technical specifications

  • Antigen: CD44v6
  • Clone: REA706
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CDw44, Epican, ECMR-III, PGP-I, CSPG9, EMCR III, HCELL, HUTCH-I, H-CAM
  • Entrez Gene ID: 960
  • Molecular mass of antigen [kDa]: 79
  • Distribution of antigen: hematopoietic cells, fibroblasts
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, PE-Vio770, APC-Vio770, Biotin, pure
Product options: 9

Product information

Size
Order no.
Price

CD44v6-APC, human

  • REA706
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-425
EUR 146,00 

CD44v6-APC, human

  • REA706
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-238
EUR 322,00 

CD44v6-PE-Vio770, human

  • REA706
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-426
EUR 146,00 

CD44v6-PE-Vio770, human

  • REA706
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-239
EUR 322,00 

CD44v6-APC-Vio770, human

  • REA706
  • 1:50
  • For research use only
for 30
tests
(1)
130-111-427
EUR 129,00 

CD44v6-APC-Vio770, human

  • REA706
  • 1:50
  • For research use only
for 100
tests
(1)
130-111-240
EUR 308,00 

CD44v6-Biotin, human

  • REA706
  • 1:50
  • For research use only
for 30
tests
(1)
130-112-769
EUR 86,00 

CD44v6-Biotin, human

  • REA706
  • 1:50
  • For research use only
for 100
tests
(1)
130-112-580
EUR 252,00 

CD44v6 pure, human

  • REA706
  • For research use only
100 µg in 1 mL
130-111-241
EUR 144,00 

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