CD44 antibodies, mouse

CD44 antibodies, mouse

Clone: IM7.8.1 | Dilution: 1:50
Mouse CD44 is also known as Pgp-1, HCELL, HUTCH-I, HCAM, HERMES, and Ly-24. Clone IM7 reacts with murine CD44, an 80–95 kDa membrane glycoprotein. It is expressed by a variety of hematopoetic and non-hematopoetic cells. Different isoforms are generated by alternative splicing. Clone IM7 reacts with all isoforms and both allelic forms of CD44. CD44 functions as a receptor for hyaluronic acid (HA) and mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 expression is upregulated on naive T cells upon activation and high CD44 expression is maintained on memory T cells. Therefore, CD44 is often used to discriminate CD44
high
antigen-experienced T cells from CD44
low
(CD62L
+
) naive T cells.

Alternative Names

HERMES, Ly-24, Pgp-1, CD44s, EMCR III, H-CAM

Technical specifications

  • Antigen: CD44
  • Clone: IM7.8.1
  • Isotype: rat IgG2bκ
  • Isotype control: Rat IgG2b – isotype control antibodies
  • Alternative names of antigen: HERMES, Ly-24, Pgp-1, CD44s, EMCR III, H-CAM
  • Entrez Gene ID: 12505
  • Molecular mass of antigen [kDa]: 83
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon, human, pig, cow, horse, cat, dog
  • Distribution of antigen: bone marrow, cancer stem cells, CNS cells, endothelial cells, epithelial cells, kidney, leukocytes, lymphocytes, mesenchymal stem cells, myeloid cells, plasma cells, ES and iPS cells, red blood cells, skeletal muscle, skin, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBlue
Product options: 2

Product information

Size
Order no.
Price

CD44-VioBlue, mouse

  • IM7.8.1
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-495
EUR 120,00 

CD44-VioBlue, mouse

  • IM7.8.1
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-531
EUR 298,00