CD43 antibodies, human

CD43 antibodies, human

Clone: REA833 | Dilution: 1:50
Clone REA833 recognizes the human CD43 antigen, also known as leukosialin, a cell surface sialoglycoprotein that is involved in cell adhesion, differentiation, and activation. The CD43 antigen is expressed on most leukocytes, i.e., T cells, NK cells, granulocytes, monocytes, and macrophages, on hematopoietic stem cells and on platelets, but not on erythrocytes. Among B cells, CD43 is expressed on activated B cells and plasma cells but not on resting B cells, e.g., naive B cells. In bone marrow, CD43 is found on pro–B cells but is down-regulated during transition to the pre–B cell stage. CD43 is expressed on different myeloid and lymphoid tumors, including some B cell malignancies.
Additional information: Clone REA833 displays negligible binding to Fc receptors.

Alternative names

Spn, Leukosialin, GALGP, gpL115, Lsn, Sialophorin

Technical specifications

  • Antigen: CD43
  • Clone: REA833
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Spn, Leukosialin, GALGP, gpL115, Lsn, Sialophorin
  • Entrez Gene ID: 6693
  • Molecular mass of antigen [kDa]: 38
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: B cells, basophils, bone marrow, granulocytes, lymphocytes, macrophages, megakaryocytes, mesenchymal stem cells, monocytes, neutrophils, NK cells, plasma cells, platelets, red blood cells, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Whitehead, A. S. et al. (1989) Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndrome. Proc. Natl. Acad. Sci. U.S.A. 86(8): 2819-2823
    2. Shelley, C. S. et al. (1990) Structure of the human sialophorin (CD43) gene. Identification of features atypical of genes encoding integral membrane proteins. Biochem. J. 270(3): 569-576
    3. Kudo, S. et al. (1991) A short, novel promoter sequence confers the expression of human leukosialin, a major sialoglycoprotein on leukocytes. J. Biol. Chem. 266(13): 8483-8489
Product options: 19
130-114-749

CD43-FITC, human

for 30
tests
(1)
EUR 90,00 
130-114-592

CD43-FITC, human

for 100
tests
(1)
EUR 220,00 
130-114-750

CD43-PE, human

for 30
tests
(1)
EUR 110,00 
130-114-593

CD43-PE, human

for 100
tests
(1)
EUR 265,00 
130-114-751

CD43-APC, human

for 30
tests
(1)
EUR 110,00 
130-114-594

CD43-APC, human

for 100
tests
(1)
EUR 265,00 
130-114-755

CD43-VioBlue, human

for 30
tests
(1)
EUR 115,00 
130-114-598

CD43-VioBlue, human

for 100
tests
(1)
EUR 275,00 
130-114-756

CD43-VioGreen, human

for 30
tests
(1)
EUR 115,00 
130-114-599

CD43-VioGreen, human

for 100
tests
(1)
EUR 275,00 
130-114-757

CD43-PE-Vio615, human

for 30
tests
(1)
EUR 120,00 
130-114-600

CD43-PE-Vio615, human

for 100
tests
(1)
EUR 290,00 
130-114-595

CD43-PE-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-114-753

CD43-APC-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-114-596

CD43-APC-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-114-754

CD43-PerCP-Vio700, human

for 30
tests
(1)
EUR 120,00 
130-114-597

CD43-PerCP-Vio700, human

for 100
tests
(1)
EUR 290,00 
130-114-748

CD43-Biotin, human

for 30
tests
(1)
EUR 90,00 
130-114-591

CD43-Biotin, human

for 100
tests
(1)
EUR 220,00