CD4 antibodies, human

CD4 antibodies, human

Clone: REA623 | Dilution: 1:11
Clone REA623 recognizes the human CD4 antigen, a 55 kDa single-pass type I membrane protein, also known as T4/Leu-3. CD4 is highly expressed on T helper cells and at a lower level on monocytes and dendritic cells. It is involved in the recognition of MHC class II/peptide complexes by the TCR heterodimers and is the receptor for the human immunodeficiency virus (HIV).
Additional information: Clone REA623 displays negligible binding to Fc receptors.

Alternative Names

T4, Leu-3, CD4mut

Technical specifications

  • Antigen: CD4
  • Clone: REA623
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: T4, Leu-3, CD4mut
  • Entrez Gene ID: 920
  • Molecular mass of antigen [kDa]: 48
  • Distribution of antigen: monocytes, T cells, thymocytes, T helper cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, Biotin

REAfinity clone is tested against different known clones, in a blocking experiment, to identify whether they recognize completely overlapping (++), partially overlapping (+), or completely different epitopes (-). In a blocking experiment, cells are incubated with an excess of purified unconjugated REAfinity clone followed by staining with conjugated form of the other known clones. 

Other clonesOverlap in epitope recognition with REA623
RPA-T4-
SK3++
OKT4-
Vit4.3-
M-T466++
M-T321++
Product options: 2

Product information

Size
Order no.
Price

CD4-Biotin, human

  • REA623
  • 1:11
  • For research use only
for 30
tests
(1)
130-109-529
EUR 85,00 

CD4-Biotin, human

  • REA623
  • 1:11
  • For research use only
for 100
tests
(1)
130-109-450
EUR 248,00 

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