CD39 antibodies, human

CD39 antibodies, human

Clone: MZ18-23C8 | Dilution: 1:11
The CD39 antibody specifically recognizes the membrane-bound human CD39 antigen, which is expressed on an effector/memory-like subset of FoxP3
+
regulatory T cells. CD39 is an ectonucleotidase and catalyzes the hydrolysis of extracellular nucleotides, for example, ATP. In concert with CD73, which is an ecto-5’-nucleotidase, this can lead to the production of adenosine. High extracellular ATP concentrations indicate tissue injury and cell death and induce various pro-inflammatory responses in immune cells.
Through its enzymatic activity, CD39 can contribute to the suppressive function of regulatory T cells, for example, by eliminating extracellular ATP or by generating adenosine, which has suppressive effects on various immune cells.

Alternative names

Entpd1, ATPDase, NTPDase-1, SPG64, EC3.6.1.5, gp80

Technical specifications

  • Antigen: CD39
  • Clone: MZ18-23C8
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Entpd1, ATPDase, NTPDase-1, SPG64, EC3.6.1.5, gp80
  • Entrez Gene ID: 953
  • Molecular mass of antigen [kDa]: 58
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, Langerhans cells, lymphocytes, macrophages, monocytes, NK cells, placenta, platelets, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin, pure
  • Selected references

    1. Borsellino, G. et al. (2007)
      Expression of ectonucleotidase CD39 by FoxP3
      +
      reg cells: hydrolysis of extracellular ATP and immune suppression.
      Blood 110: 1225-1232
Product options: 14
130-099-383

CD39-FITC, human

for 30
tests
(1)
EUR 90,00 
130-093-502

CD39-FITC, human

for 100
tests
(1)
EUR 220,00 
130-099-926

CD39-PE, human

for 30
tests
(1)
EUR 110,00 
130-093-503

CD39-PE, human

for 100
tests
(1)
EUR 265,00 
130-100-459

CD39-APC, human

for 30
tests
(1)
EUR 110,00 
130-093-504

CD39-APC, human

for 100
tests
(1)
EUR 265,00 
130-106-595

CD39-VioBlue, human

for 30
tests
(1)
EUR 115,00 
130-106-551

CD39-VioBlue, human

for 100
tests
(1)
EUR 275,00 
130-100-220

CD39-PE-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-100-227

CD39-PE-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-105-584

CD39-APC-Vio770, human

for 30
tests
(1)
EUR 120,00 
130-105-532

CD39-APC-Vio770, human

for 100
tests
(1)
EUR 290,00 
130-093-505

CD39-Biotin, human

for 100
tests
(1)
EUR 220,00 
130-093-506

CD39 pure, human

100 µg in 1 mL
EUR 198,00