CD357 (GITR) antibodies, mouse

CD357 (GITR) antibodies, mouse

Clone: REA980 | Dilution: 1:50
Clone REA980 recognizes the mouse CD357 antigen, also known as glucocorticoid-induced TNF-receptor (GITR) or TNFRSF18. CD357 is a member of the TNF receptor superfamily. It is expressed at low levels on resting T lymphocytes and at high levels on CD4
+
CD25
+
regulatory T cells (Tregs). Activation of T cells upregulates CD357 expression. Interaction of CD357 (GTITR) with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation. CD357 plays an important role in the function of CD4
+
CD25
+
Tregs.
Additional information: Clone REA980 displays negligible binding to Fc receptors.

Alternative Names

GITR, TNFRSF18, AITR

Technical specifications

  • Antigen: CD357 (GITR)
  • Clone: REA980
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: GITR, TNFRSF18, AITR
  • Entrez Gene ID: 21936
  • Molecular mass of antigen [kDa]: 23
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, VioBright 515, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD357 (GITR)-FITC, mouse

  • REA980
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-425
EUR 45,00 

CD357 (GITR)-FITC, mouse

  • REA980
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-361
EUR 196,00 

CD357 (GITR)-PE, mouse

  • REA980
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-426
EUR 57,00 

CD357 (GITR)-PE, mouse

  • REA980
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-362
EUR 224,00 

CD357 (GITR)-APC, mouse

  • REA980
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-427
EUR 83,00 

CD357 (GITR)-APC, mouse

  • REA980
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-363
EUR 259,00 

CD357 (GITR)-PE-Vio615, mouse

  • REA980
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-429
EUR 101,00 

CD357 (GITR)-PE-Vio615, mouse

  • REA980
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-365
EUR 298,00 

CD357 (GITR)-VioBright 515, mouse

  • REA980
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-428
EUR 107,00 

CD357 (GITR)-VioBright 515, mouse

  • REA980
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-364
EUR 398,00 

CD357 (GITR)-Biotin, mouse

  • REA980
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-116-424
EUR 32,00 

CD357 (GITR)-Biotin, mouse

  • REA980
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-116-360
EUR 147,00 

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