CD352 (NTB-A) antibodies, human

CD352 (NTB-A) antibodies, human

Clone: REA339 | Dilution: 1:11
Clone REA339 recognizes the human CD352 antigen, a 60 kDa single-pass type I membrane protein also known as SLAM family member 6 (SLAM6) or NK-, T-, and B-cell antigen (NTB-A). CD352 belongs to the CD2 subfamily of the immunoglobulin superfamily and is expressed on NK, T, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases. Monoclonal antibody-mediated cross-linking of CD352 results in the induction of NK-mediated cytotoxicity. CD352 also triggers cytolytic activity only in NK cells expressing high surface densities of natural cytotoxicity receptors. This suggests that CD352 may function as a coreceptor in the process of NK cell activation. Importantly, analysis of NK cells derived from patients with X-linked lymphoproliferative disease showed that the lack of SH2D1A protein profoundly affects the function of CD352.
Additional information: Clone REA339 displays negligible binding to Fc receptors.

Alternative Names

SLAMF6, KALI, KALIb, LY108, NTB-A, NTBA, SF2000, SLAM6, TCOM

Technical specifications

  • Antigen: CD352 (NTB-A)
  • Clone: REA339
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: SLAMF6, KALI, KALIb, LY108, NTB-A, NTBA, SF2000, SLAM6, TCOM
  • Entrez Gene ID: 114836
  • Molecular mass of antigen [kDa]: 35
  • Distribution of antigen: NK cells, B cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD352 (NTB-A)-FITC, human

  • REA339
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-593
EUR 65,00 

CD352 (NTB-A)-FITC, human

  • REA339
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-541
EUR 255,00 

CD352 (NTB-A)-PE, human

  • REA339
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-594
EUR 85,00 

CD352 (NTB-A)-PE, human

  • REA339
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-542
EUR 300,00 

CD352 (NTB-A)-APC, human

  • REA339
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-595
EUR 111,00 

CD352 (NTB-A)-APC, human

  • REA339
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-543
EUR 326,00 

CD352 (NTB-A)-PE-Vio770, human

  • REA339
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-596
EUR 111,00 

CD352 (NTB-A)-PE-Vio770, human

  • REA339
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-544
EUR 326,00 

CD352 (NTB-A)-APC-Vio770, human

  • REA339
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-597
EUR 98,00 

CD352 (NTB-A)-APC-Vio770, human

  • REA339
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-545
EUR 313,00 

CD352 (NTB-A)-Biotin, human

  • REA339
  • 1:11
  • For research use only
for 30
tests
(1)
130-105-592
EUR 65,00 

CD352 (NTB-A)-Biotin, human

  • REA339
  • 1:11
  • For research use only
for 100
tests
(1)
130-105-540
EUR 255,00 

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