CD329 (Siglec-9) antibodies, human

CD329 (Siglec-9) antibodies, human

Clone: REA492 | Dilution: 1:11
Clone REA492 recognizes the human CD329 antigen, a single-pass type I membrane protein also known as sialic acid-binding Ig-like lectin 9 (Siglec-9). Siglecs are characterized by an amino-terminal V-set immunoglobulin domain that binds to sialic acid residues, followed by a variable number of C2-set immunoglobulin-like domains. CD329 is expressed quite broadly among human blood leukocytes, being found on monocytes, neutrophils, B cells, NK cells, and minor subsets of T cells. Ligation of CD329 induced apoptosis in adult neutrophils in a caspase-dependent manner; in contrast, its activation under inflammatory conditions resulted in a caspase-independent autophagic type of cell death. These disparate actions implicate a unique role for CD329 in modulating cell survival under inflammatory and basal conditions.
Additional information: Clone REA492 displays negligible binding to Fc receptors.

Alternative Names

CDw329, FOAP-9, OBBP-LIKE, Siglec-9

Technical specifications

  • Antigen: CD329 (Siglec-9)
  • Clone: REA492
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CDw329, FOAP-9, OBBP-LIKE, Siglec-9
  • Entrez Gene ID: 27180
  • Molecular mass of antigen [kDa]: 48
  • Distribution of antigen: B cells, granulocytes, leukocytes, macrophages, monocytes, T cells, lymphocytes, neutrophils, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, PE-Vio770, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD329 (Siglec-9)-VioBright FITC, human

  • REA492
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-651
EUR 154,00 

CD329 (Siglec-9)-VioBright FITC, human

  • REA492
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-607
EUR 308,00 

CD329 (Siglec-9)-PE, human

  • REA492
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-648
EUR 112,00 

CD329 (Siglec-9)-PE, human

  • REA492
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-604
EUR 296,00 

CD329 (Siglec-9)-PE-Vio770, human

  • REA492
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-650
EUR 146,00 

CD329 (Siglec-9)-PE-Vio770, human

  • REA492
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-606
EUR 322,00 

CD329 (Siglec-9)-Biotin, human

  • REA492
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-647
EUR 86,00 

CD329 (Siglec-9)-Biotin, human

  • REA492
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-603
EUR 252,00 

Related products

3 products available