CD32 antibodies, human

CD32 antibodies, human

Clone: 2E1 | Dilution: 1:11
FcγRII (CD32) is a 40 kDa low affinity receptor for the Fc fragment of aggregated IgG. Due to alternative splicing three different isoforms of CD32 are expressed on hematopoietic cells: FcRIIA, FcRIIB, and FcRIIC. The cytoplasmic domains of FcRIIA and FcRIIC contain an activatory ITAM motif whereas FcRIIB is an inhibitory receptor containing an ITIM motif. Different isoforms of CD32 are expressed on B cells, monocytes, dendritic cells, granulocytes, and platelets. The monoclonal antibody 2E1 recognizes all isoforms of CD32 without blocking the binding of immune complexes.

Alternative Names

FCGR2A, FCGR2B, FCGR2C, FcγRII

Technical specifications

  • Antigen: CD32
  • Clone: 2E1
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: FCGR2A, FCGR2B, FCGR2C, FcγRII
  • Entrez Gene ID: 2212
  • Molecular mass of antigen [kDa]: 31
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    , baboon, horse
  • Distribution of antigen: B cells, basophils, dendritic cells, endothelial cells, eosinophils, granulocytes, Langerhans cells, leukocytes, lymphocytes, macrophages, monocytes, myeloid cells, neutrophils, NK cells, placenta, plasma cells, platelets
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin
Product options: 8

Product information

Size
Order no.
Price

CD32-FITC, human

  • 2E1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-518
EUR 187,00 

CD32-PE, human

  • 2E1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-521
EUR 240,00 

CD32-APC, human

  • 2E1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-525
EUR 256,00 

CD32-VioBlue, human

  • 2E1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-511
EUR 245,00 

CD32-PE-Vio770, human

  • 2E1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-506
EUR 283,00 

CD32-APC-Vio770, human

  • 2E1
  • 1:11
  • For research use only
for 30
tests
(1)
130-100-448
EUR 101,00 

CD32-APC-Vio770, human

  • 2E1
  • 1:11
  • For research use only
for 100
tests
(1)
130-100-445
EUR 278,00 

CD32-Biotin, human

  • 2E1
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-509
EUR 240,00 

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