CD310 (VEGFR-3) antibodies, mouse

CD310 (VEGFR-3) antibodies, mouse

Clone: REA834 | Dilution: 1:50
Clone REA843 recognizes the mouse CD310 antigen, a member of the receptor tyrosine kinase family. This 195 kDa molecule is also known as Flt-4 or VEGFR-3. During early embryogenesis all endothelial cells express CD310, while in the adult tissues CD310 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. CD310 expression is also induced upon tumor angiogenesis. VEGF-C and VEGF-D are ligands for CD310.
Additional information: Clone REA834 displays negligible binding to Fc receptors.

Alternative names

FLT4, Chy, FLT-4, VEGFR-3

Technical specifications

  • Antigen: CD310 (VEGFR-3)
  • Clone: REA834
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: FLT4, Chy, FLT-4, VEGFR-3
  • Entrez Gene ID: 14257
  • Molecular mass of antigen [kDa]: 151
  • Distribution of antigen: endothelial cells, tumor cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, Biotin
  • Selected references

    1. Galland, F. et al. (1992) Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene. Genomics 13(2): 475-478
    2. Kubo, H. et al. (2000) Involvement of vascular endothelial growth factor receptor-3 in maintance of integrity of endothelial cell lining during tumor angiogenesis. Blood 2(96): 546-553
    3. Zhang, L. et al. (2010) VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis. Cell Res. 20(12): 1319-1331
Product options: 10
30 µg in 200 µL (1)
EUR 55,00 
150 µg in 1 mL (1)
EUR 155,00 
30 µg in 200 µL (1)
EUR 90,00 
150 µg in 1 mL (1)
EUR 265,00 
30 µg in 200 µL (1)
EUR 90,00 
150 µg in 1 mL (1)
EUR 265,00 
30 µg in 200 µL (1)
EUR 100,00 
150 µg in 1 mL (1)
EUR 295,00 
30 µg in 200 µL (1)
EUR 55,00 
150 µg in 1 mL (1)
EUR 155,00 

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