CD284 antibodies, human

CD284 antibodies, human

Clone: HTA125 | Dilution: 1:11
Clone HTA125 reacts with CD284, a type I transmembrane signaling receptor also known as Toll-like receptor 4 (TLR4). Toll-like receptors are a family of pattern recognition receptors detecting the presence and characteristics of an infection and induce appropriately tailored innate and adaptive immune responses. TLR4 associates with its co-receptor MD-2. Together with the lipopolysaccharide (LPS)-binding protein (LBP) and CD14, this complex is responsible for signaling upon LPS recognition. TLR4 is expressed on monocytes and myeloid dendritic cells. Low levels are expressed on B cells and granulocytes in human peripheral blood. HTA125 is able to block LPS-induced signaling and recognizes predominantly human TLR4 associated with MD-2.

Alternative Names

TLR4, ARMD10, TLR-4, TOLL

Technical specifications

  • Antigen: CD284
  • Clone: HTA125
  • Isotype: mouse IgG2aκ
  • Isotype control: Mouse IgG2a – isotype control antibodies
  • Alternative names of antigen: TLR4, ARMD10, TLR-4, TOLL
  • Entrez Gene ID: 7099
  • Molecular mass of antigen [kDa]: 93
  • Cross-reactivity: rabbit, guinea pig
  • Distribution of antigen: dendritic cells, endothelial cells, granulocytes, leukocytes, macrophages, monocytes, placenta, spleen, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
Product options: 5

Product information

Size
Order no.
Price

CD284-PE, human

  • HTA125
  • 1:11
  • For research use only
for 30
tests
(1)
130-100-378
EUR 91,00 

CD284-PE, human

  • HTA125
  • 1:11
  • For research use only
for 100
tests
(1)
130-096-237
EUR 240,00 

CD284-APC, human

  • HTA125
  • 1:11
  • For research use only
for 30
tests
(1)
130-100-150
EUR 113,00 

CD284-APC, human

  • HTA125
  • 1:11
  • For research use only
for 100
tests
(1)
130-096-236
EUR 256,00 

CD284-Biotin, human

  • HTA125
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-349
EUR 240,00 

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