CD272 (BTLA) antibodies, mouse

CD272 (BTLA) antibodies, mouse

Clone: REA224 | Dilution: 1:10
Clone REA224 recognizes the mouse CD272 antigen, which is also known as B- and T-lymphocyte attenuator (BTLA) or B- and T-lymphocyte-associated protein. CD272, an Ig domain superfamily receptor protein with similarities to cytotoxic T-lymphocyte antigen-4 and programmed death-1, is expressed on various cell types like splenic T and B cells, macrophages, NK cells, dendritic cells as well as lymph node tissues but very weakly in somatic tissues. A polymorphic tissue distribution between several mouse strains is seen. Crosslinking CD272 with antigen receptors results in downregulation of T cell activation and attenuates production of interleukin 2. CD272 deficient mice have increased specific antibody responses and enhanced incidence and severity of autoimmune disorders.
Additional information: Clone REA224 displays negligible binding to Fc receptors.

Alternative Names

BTLA, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein

Technical specifications

  • Antigen: CD272 (BTLA)
  • Clone: REA224
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: BTLA, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein
  • Entrez Gene ID: 208154
  • Molecular mass of antigen [kDa]: 31
  • Distribution of antigen: B cells, T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770
Product options: 6

Product information

Size
Order no.
Price

CD272 (BTLA)-PE, mouse

  • REA224
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-103-328
EUR 27,00 

CD272 (BTLA)-PE, mouse

  • REA224
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-689
EUR 54,00 

CD272 (BTLA)-APC, mouse

  • REA224
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-103-327
EUR 44,00 

CD272 (BTLA)-APC, mouse

  • REA224
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-688
EUR 86,00 

CD272 (BTLA)-PE-Vio770, mouse

  • REA224
  • 1:10
  • For research use only
9 µg in 300 µL (1)
130-103-326
EUR 44,00 

CD272 (BTLA)-PE-Vio770, mouse

  • REA224
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-687
EUR 86,00 

Related products

2 products available