CD262 antibodies, human

CD262 antibodies, human

Clone: DJR2-4 | Dilution: 1:11
The DJR2-4 antibody binds to death receptor 5 (DR5), member 10B of the TNF receptor superfamily (TNFRSF10B), also known as CD262, TRAIL-R2/ TRAILR2, TRICK2, KILLER, and ZTNFR9. Binding of TNF-related apoptosis-inducing ligand (TRAIL, TNFSF10, TL2, APO2L, Apo-2L) to DR5 induces apoptosis via the intracellular adaptor molecule FADD/MORT. The DR5 receptor is broadly expressed on many tumors and normal tissues. DR5 expression is upregulated by interferon α, taxotere, and paclitaxel, making DR5
+
target cells more susceptible to NK cell mediated killing.

Alternative Names

TNFRSF10B, DR5, KILLER, TRAIL-R2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9

Technical specifications

  • Antigen: CD262
  • Clone: DJR2-4
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: TNFRSF10B, DR5, KILLER, TRAIL-R2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
  • Entrez Gene ID: 8795
  • Molecular mass of antigen [kDa]: 42
  • Distribution of antigen: heart, leukocytes, liver, lung, ovary, pancreas, placenta, spleen, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
Product options: 3

Product information

Size
Order no.
Price

CD262-PE, human

  • DJR2-4
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-260
EUR 240,00 

CD262-APC, human

  • DJR2-4
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-249
EUR 256,00 

CD262-Biotin, human

  • DJR2-4
  • 1:11
  • For research use only
for 100
tests
(1)
130-097-303
EUR 240,00 

Related products

2 products available