CD255 (TWEAK) antibodies, mouse

CD255 (TWEAK) antibodies, mouse

Clone: MTW-1 | Dilution: 1:10
The monoclonal antibody MTW-1 reacts with mouse CD255 also known as TWEAK which is a type II transmembrane member of the TNF superfamily with a molecular weight of 27 kDa. It is expressed on a variety of cell types and binds to the TWEAK receptor, Fn14. It functions as an inducer of apoptosis in some cell types, promotes angiogenesis and the proliferation of endothelial cells. Furthermore, it is implicated in the induction of inflammatory cytokines.

Alternative names

TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK

Technical specifications

  • Antigen: CD255 (TWEAK)
  • Clone: MTW-1
  • Isotype: rat IgG1κ
  • Isotype control: Rat IgG1 – isotype control antibodies
  • Alternative names of antigen: TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK
  • Entrez Gene ID: 21944
  • Molecular mass of antigen [kDa]: 27
  • Distribution of antigen: brain, CNS cells, endothelial cells, fibroblasts, heart, lung, lymphocytes, monocytes, ovary, pancreas, skeletal muscle, small intestine, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, Biotin, PE
  • Selected references

    1. Schneider, P. et al. (1999) TWEAK can induce cell death via endogenous TNF and TNF receptor 1. Eur. J. Immunol. 29(6): 1785-1792
    2. Nakayama, M. et al. (2003) Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies. Biochem. Biophys. Res. Commun. 306(4): 819-825
    3. Lynch, C. N. et al. (1999) TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 274: 8455-8459
Product options: 3
30 µg in 1 mL (1)
EUR 82,00 
30 µg in 1 mL (1)
EUR 82,00 
30 µg in 1 mL (1)
EUR 41,00