CD253 antibodies, mouse

CD253 antibodies, mouse

Clone: REA1030 | Dilution: 1:50
Clone REA1030 recognizes the mouse CD253 antigen, a type 2 transmembrane protein also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR).
Additional information: Clone REA1030 displays negligible binding to Fc receptors.

Alternative Names

TNFSF10, APO2L, Ly81, TL2, TRAIL

Technical specifications

  • Antigen: CD253
  • Clone: REA1030
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TNFSF10, APO2L, Ly81, TL2, TRAIL
  • Entrez Gene ID: 22035
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: B cells, dendritic cells, monocytes, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected References

    1. Wiley, S. R. et al. (1995) Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3(6): 673-682
    2. Hofmann, K. (1999) The modular nature of apoptotic signaling proteins. Cell. Mol. Life Sci. 55(8-9): 1113-1128
    3. Locksley, R. M. et al. (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104(4): 487-501
Product options: 17

Product information

Size
Order no.
Price

CD253-FITC, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-559
EUR 40,00 

CD253-PE, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-560
EUR 80,00 

CD253-PE, mouse

  • REA1030
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-411
EUR 230,00 

CD253-APC, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-561
EUR 80,00 

CD253-APC, mouse

  • REA1030
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-412
EUR 230,00 

CD253-VioBlue, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-562
EUR 95,00 

CD253-VioBlue, mouse

  • REA1030
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-413
EUR 275,00 

CD253-PE-Vio615, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-563
EUR 100,00 

CD253-PE-Vio615, mouse

  • REA1030
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-414
EUR 295,00 

CD253-PE-Vio770, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-564
EUR 100,00 

CD253-PE-Vio770, mouse

  • REA1030
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-415
EUR 295,00 

CD253-APC-Vio770, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-565
EUR 100,00 

CD253-PerCP-Vio700, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-566
EUR 100,00 

CD253-VioBright 515, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-567
EUR 145,00 

CD253-VioBright 515, mouse

  • REA1030
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-418
EUR 420,00 

CD253-Biotin, mouse

  • REA1030
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-117-568
EUR 40,00 

CD253-Biotin, mouse

  • REA1030
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-117-419
EUR 120,00