CD253 antibodies, mouse

CD253 antibodies, mouse

Clone: N2B2 | Dilution: 1:10
Clone N2B2 reacts with murine CD253, a type 2 transmembrane protein, also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR). The N2B2 antibody is reported to block CD253-mediated NK cell cytotoxicity
in vitro
.

Alternative Names

TNFSF10, APO2L, Ly81, TL2, TRAIL

Technical specifications

  • Antigen: CD253
  • Clone: N2B2
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: TNFSF10, APO2L, Ly81, TL2, TRAIL
  • Entrez Gene ID: 22035
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: B cells, dendritic cells, gut, kidney, lung, monocytes, NK cells, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, Biotin
Product options: 5

Product information

Size
Order no.
Price

CD253-FITC, mouse

  • N2B2
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-477
EUR 44,00 

CD253-PE, mouse

  • N2B2
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-562
EUR 54,00 

CD253-APC, mouse

  • N2B2
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-510
EUR 86,00 

CD253-VioBlue, mouse

  • N2B2
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-102-406
EUR 113,00 

CD253-Biotin, mouse

  • N2B2
  • 1:10
  • For research use only
30 µg in 1 mL (1)
130-101-914
EUR 32,00 

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