CD253 antibodies, mouse

CD253 antibodies, mouse

Clone: N2B2 | Dilution: 1:10
Clone N2B2 reacts with murine CD253, a type 2 transmembrane protein, also known as TNF-related apoptosis-inducing ligand (TRAIL), APO-2 ligand (APO-2L), or TNF ligand superfamily member 10 (TNFSF10). CD253 is expressed on a variety of cells of the innate and adaptive immune system, including natural killer (NK) cells. Often expression is induced or upregulated upon activation. CD253 can trigger apoptosis through trimerization of death receptor DR5 (TRAILR). The N2B2 antibody is reported to block CD253-mediated NK cell cytotoxicity
in vitro
.

Alternative Names

TNFSF10, APO2L, Ly81, TL2, TRAIL

Technical specifications

  • Antigen: CD253
  • Clone: N2B2
  • Isotype: rat IgG2aκ
  • Isotype control: Rat IgG2a – isotype control antibodies
  • Alternative names of antigen: TNFSF10, APO2L, Ly81, TL2, TRAIL
  • Entrez Gene ID: 22035
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: B cells, dendritic cells, gut, kidney, lung, monocytes, NK cells, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, Biotin
Product options: 5
130-102-477

CD253-FITC, mouse

30 µg in 1 mL (1)
EUR 40,00 
130-102-562

CD253-PE, mouse

30 µg in 1 mL (1)
EUR 80,00 
130-102-510

CD253-APC, mouse

30 µg in 1 mL (1)
EUR 80,00 
130-102-406

CD253-VioBlue, mouse

30 µg in 1 mL (1)
EUR 95,00 
130-101-914

CD253-Biotin, mouse

30 µg in 1 mL (1)
EUR 40,00