CD252 (OX40L) antibodies, rat

CD252 (OX40L) antibodies, rat

Clone: ATM-2 | Dilution: 1:10
Clone ATM-2 recognizes the rat CD252 antigen, a member of the TNF ligand superfamily, also known as OX40 ligand (OX40L) or tumor necrosis factor ligand superfamily member 4 (TNSFSF4). CD252 is constitutively expressed by splenic dendritic cells and can be upregulated on splenic B cells via stimulation with LPS. Expression of the cognate receptor CD134 (OX40) is found predominantly on activated T cells. CD252/CD134 interaction promotes the proliferation and survival of effector T cells, modulates cytokine production, suppresses the activity of natural regulatory T cells, and inhibits the generation of inducible regulatory T cells.

Alternative names

TNFSF4, OX40L

Technical specifications

  • Antigen: CD252 (OX40L)
  • Clone: ATM-2
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: TNFSF4, OX40L
  • Entrez Gene ID: 89814
  • Molecular mass of antigen [kDa]: 22
  • Distribution of antigen: dendritic cells, B cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected references

    1. Satake, Y. et al. (2000) Characterization of rat OX40 ligand by monoclonal antibody. Biochem. Biophys. Res. Commun. 270(3): 1041-1048
    2. Paterson, D. J. et al. (1987) Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol. Immunol. 24(12): 1281-1290
    3. Ishii, N. et al. (2010) OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology. Adv. Immunol. 105: 63-98
Product options: 5
9 µg in 300 µL
EUR 27,00 
30 µg in 1 mL
EUR 80,00 
9 µg in 300 µL
EUR 44,00 
30 µg in 1 mL
EUR 80,00 
30 µg in 1 mL
EUR 40,00 

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