CD25 antibodies, human

CD25 antibodies, human

Clone: 3G10 | Dilution: 1:11
Clone 3G10 recognizes the human CD25 glycoprotein, also known as the low-affinity interleukin-2 receptor alpha chain (IL-2Rα). CD25 is expressed on activated T and B cells, on macrophages, and on a subset of non-activated CD4
+
regulatory T cells. Clone 3G10 recognizes epitope region A.

Alternative Names

IL2RA, IDDM10, IL2R, TCGFR, p55, IL-2Rα, Tac

Technical specifications

  • Antigen: CD25
  • Clone: 3G10
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: IL2RA, IDDM10, IL2R, TCGFR, p55, IL-2Rα, Tac
  • Entrez Gene ID: 3559
  • Molecular mass of antigen [kDa]: 55
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: B cells, basophils, lymphocytes, macrophages, monocytes, myeloid cells, NK cells, osteoblasts, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected References

    1. Lee, S. H. et al. (2012) Cutting edge: a novel mechanism bridging innate and adaptive immunity: IL-12 induction of CD25 to form high-affinity IL-2 receptors on NK cells. J. Immunol. 189(6): 2712-2716
    2. Goudy, K. et al. (2013) Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity. Clin. Immunol. 146(3): 248-261

Related products

2 products available
Product options: 4

Product information

Size
Order no.
Price

CD25-APC, human

  • 3G10
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-439
EUR 113,00 

CD25-APC, human

  • 3G10
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-435
EUR 255,00 

CD25-Biotin, human

  • 3G10
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-431
EUR 74,00 

CD25-Biotin, human

  • 3G10
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-429
EUR 236,00