CD243 (ABCB1) antibodies, human

CD243 (ABCB1) antibodies, human

Clone: REA495 | Dilution: 1:11
Clone REA495 recognizes the human CD243 antigen, a multi-pass membrane protein which is also known as multidrug resistance protein 1 (MDR1), ATP-binding cassette sub-family B member 1 (ABCB1), or P-glycoprotein 1. CD243 is a member of the ATP-binding cassette (ABC) transporter superfamily and plays an important role in the development of multidrug resistance (MDR) in cancer cells. This transporter utilizes energy from ATP hydrolysis for the efflux of a variety of chemically dissimilar amphipathic compounds, including anticancer drugs. CD243 is extensively distributed and expressed in the intestinal epithelium, in liver cells, in the cells of the proximal tubule of the kidney and in the capillary endothelial cells composing the blood-brain barrier and blood-testis barrier. It is also expressed on hematopoietic stem cells, T cells, B cells, and NK cells as well as on many multidrug resistant neoplastic cells.
Additional information: Clone REA495 displays negligible binding to Fc receptors.

Alternative Names

ABCB1, ABC20, CLCS, GP170, MDR-1, P-GP, PGY1

Technical specifications

  • Antigen: CD243 (ABCB1)
  • Clone: REA495
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ABCB1, ABC20, CLCS, GP170, MDR-1, P-GP, PGY1
  • Entrez Gene ID: 5243
  • Molecular mass of antigen [kDa]: 142
  • Distribution of antigen: B cells, endothelial cells, hematopoietic stem cells, NK cells, T cells, small intestine, myeloid leukemia cells, bile duct, brain, breast, kidney, liver, other
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
Product options: 12

Product information

Size
Order no.
Price

CD243 (ABCB1)-VioBright FITC, human

  • REA495
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-529
EUR 154,00 

CD243 (ABCB1)-VioBright FITC, human

  • REA495
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-476
EUR 308,00 

CD243 (ABCB1)-PE, human

  • REA495
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-525
EUR 112,00 

CD243 (ABCB1)-PE, human

  • REA495
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-472
EUR 296,00 

CD243 (ABCB1)-APC, human

  • REA495
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-526
EUR 146,00 

CD243 (ABCB1)-APC, human

  • REA495
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-473
EUR 322,00 

CD243 (ABCB1)-PE-Vio770, human

  • REA495
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-527
EUR 146,00 

CD243 (ABCB1)-PE-Vio770, human

  • REA495
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-474
EUR 322,00 

CD243 (ABCB1)-APC-Vio770, human

  • REA495
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-528
EUR 129,00 

CD243 (ABCB1)-APC-Vio770, human

  • REA495
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-475
EUR 308,00 

CD243 (ABCB1)-Biotin, human

  • REA495
  • 1:11
  • For research use only
for 30
tests
(1)
130-107-524
EUR 86,00 

CD243 (ABCB1)-Biotin, human

  • REA495
  • 1:11
  • For research use only
for 100
tests
(1)
130-107-471
EUR 252,00 

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