CD229 (Ly-9) antibodies, human

CD229 (Ly-9) antibodies, human

Clone: Hly9.1.25 | Dilution: 1:11
Clone Hly9.1.25 reacts with CD229, a type I transmembrane glycoprotein belonging to the CD150 subfamily of leukocyte receptors of the Ig superfamily. CD229 has four extracellular Ig domains and a cytoplasmic domain containing two copies of the tyrosine-based motif (T-I/V-Y-x-x-V/I). Via this unique motif, CD229 interacts with SH2-binding phosphatases and the adapter molecules SAP, EAT-2, and Grb2. Expression of CD229 is found on T cells, B cells, NK cells, and thymocytes. CD229 interacts homophilically via its N-terminal V-like domain and is involved in enhancing T cell activation and Tʜ2 polarization.

Alternative names

Ly-9, SLAMF3, hly9, mLY9

Technical specifications

  • Antigen: CD229 (Ly-9)
  • Clone: Hly9.1.25
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: Ly-9, SLAMF3, hly9, mLY9
  • Entrez Gene ID: 4063
  • Molecular mass of antigen [kDa]: 67
  • Distribution of antigen: B cells, T cells, NK cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Martín, M. et al. (2005) Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229. J. Immunol. 174: 5977-5986
    2. Romero, X. et al. (2005) CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J. Immunol. 174(11): 7033-7042
    3. Romero, X. et al. (2004) Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4). Tissue Antigens 64(2): 132-144
Product options: 8
130-100-112

CD229 (Ly-9)-PE, human

for 30
tests
EUR 110,00 
130-100-113

CD229 (Ly-9)-PE, human

for 100
tests
EUR 265,00 
130-100-114

CD229 (Ly-9)-APC, human

for 30
tests
EUR 110,00 
130-100-115

CD229 (Ly-9)-APC, human

for 100
tests
EUR 265,00 
130-100-020

CD229 (Ly-9)-PE-Vio770, human

for 30
tests
EUR 120,00 
130-100-021

CD229 (Ly-9)-PE-Vio770, human

for 100
tests
EUR 290,00 
130-100-031

CD229 (Ly-9)-Biotin, human

for 30
tests
EUR 90,00 
130-100-032

CD229 (Ly-9)-Biotin, human

for 100
tests
EUR 220,00