CD209 (DC-SIGN) antibodies, human

CD209 (DC-SIGN) antibodies, human

Clone: DCN47.5 | Dilution: 1:11
Clone DCN47.5 recognizes CD209 (Dendritic Cell Specific ICAM-3 Grabbing Non-integrin, DC-SIGN), a type II c-type lectin expressed in dermal and mucous tissue, lymphoid tissue such as tonsil, lymph node, spleen, and on monocyte-derived DCs (MoDCs). It is not expressed on DC subsets in peripheral blood, except for a subpopulation of CD14
+
cells with a DC-like phenotype.
DC-SIGN acts as an adhesion receptor to facilitate interactions between DCs and T cells or DCs and endothelial cells. In addition, it serves as an antigen receptor mediating internalization of ligands for antigen presentation, binding virus such as HIV, HCMV, or Ebola as well as parasites, bacteria, or yeast.
HIV-1 uses this feature of DC-SIGN for efficient in
-trans
infection of CD4
+
T cells.

Alternative Names

CDSIGN, CLEC4L, DC-SIGN

Technical specifications

  • Antigen: CD209 (DC-SIGN)
  • Clone: DCN47.5
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CDSIGN, CLEC4L, DC-SIGN
  • Entrez Gene ID: 30835
  • Molecular mass of antigen [kDa]: 46
  • Distribution of antigen: dendritic cells, endothelial cells, macrophages, skin, spleen
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, Biotin, pure
Product options: 14

Product information

Size
Order no.
Price

CD209 (DC-SIGN)-FITC, human

  • DCN47.5
  • 1:11
  • For research use only
for 30
tests
(1)
130-100-086
EUR 74,00 

CD209 (DC-SIGN)-FITC, human

  • DCN47.5
  • 1:11
  • For research use only
for 100
tests
(1)
130-092-873
EUR 187,00 

CD209 (DC-SIGN)-PE, human

  • DCN47.5
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-707
EUR 91,00 

CD209 (DC-SIGN)-PE, human

  • DCN47.5
  • 1:11
  • For research use only
for 100
tests
(1)
130-092-869
EUR 240,00 

CD209 (DC-SIGN)-APC, human

  • DCN47.5
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-727
EUR 113,00 

CD209 (DC-SIGN)-APC, human

  • DCN47.5
  • 1:11
  • For research use only
for 100
tests
(1)
130-092-871
EUR 256,00 

CD209 (DC-SIGN)-VioBlue, human

  • DCN47.5
  • 1:11
  • For research use only
for 30
tests
(1)
130-099-977
EUR 91,00 

CD209 (DC-SIGN)-VioBlue, human

  • DCN47.5
  • 1:11
  • For research use only
for 100
tests
(1)
130-099-985
EUR 241,00 

CD209 (DC-SIGN)-PE-Vio770, human

  • DCN47.5
  • 1:11
  • For research use only
for 30
tests
(1)
130-104-240
EUR 111,00 

CD209 (DC-SIGN)-PE-Vio770, human

  • DCN47.5
  • 1:11
  • For research use only
for 100
tests
(1)
130-104-206
EUR 326,00 

CD209 (DC-SIGN)-APC-Vio770, human

  • DCN47.5
  • 1:11
  • For research use only
for 30
tests
(1)
130-101-239
EUR 98,00 

CD209 (DC-SIGN)-APC-Vio770, human

  • DCN47.5
  • 1:11
  • For research use only
for 100
tests
(1)
130-101-235
EUR 313,00 

CD209 (DC-SIGN)-Biotin, human

  • DCN47.5
  • 1:11
  • For research use only
for 100
tests
(1)
130-092-875
EUR 240,00 

CD209 (DC-SIGN) pure, human

  • DCN47.5
  • For research use only
100 µg in 1 mL
130-092-877
EUR 198,00 

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