CD207 (Langerin) antibodies, mouse

CD207 (Langerin) antibodies, mouse

Clone: REA822 | Dilution: 1:50
Clone REA822 recognizes the mouse CD207 antigen, also known as Langerin, which is a 48 kDa transmembrane type II C-type lectin containing a single carbohydrate recognition domain in its extracellular region. Langerin is specifically expressed on epidermal Langerhans cells and dermal CD103
+
dendritic cells. It displays Ca
2+
-dependent binding specificity for mannose, N-acetyl-glucosamine, and fucose and is involved in antigen recognition, uptake, and transport to the Birbeck granules, whose formation is dependent on Langerin expression. The CD207 epitope shows trypsin as well as collagenase sensitivity.
Additional information: Clone REA822 displays negligible binding to Fc receptors.

Alternative Names

Langerin

Technical specifications

  • Antigen: CD207 (Langerin)
  • Clone: REA822
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Langerin
  • Entrez Gene ID: 246278
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: dendritic cells, Langerhans cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected References

    1. Valladeau, J. et al. (2002) Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues. J. Immunol. 168(2): 782-792
    2. Idoyaga, J. et al. (2008)
      Cutting edge: Langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products
      in vivo
      .
      J. Immunol. 180(6): 3647-3650
Product options: 13

Product information

Size
Order no.
Price

CD207 (Langerin)-FITC, mouse

  • REA822
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-051
EUR 45,00 

CD207 (Langerin)-FITC, mouse

  • REA822
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-112-986
EUR 196,00 

CD207 (Langerin)-PE, mouse

  • REA822
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-052
EUR 57,00 

CD207 (Langerin)-PE, mouse

  • REA822
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-112-987
EUR 224,00 

CD207 (Langerin)-APC, mouse

  • REA822
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-053
EUR 83,00 

CD207 (Langerin)-APC, mouse

  • REA822
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-112-988
EUR 259,00 

CD207 (Langerin)-PE-Vio615, mouse

  • REA822
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-059
EUR 101,00 

CD207 (Langerin)-PE-Vio615, mouse

  • REA822
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-112-994
EUR 298,00 

CD207 (Langerin)-PE-Vio770, mouse

  • REA822
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-054
EUR 101,00 

CD207 (Langerin)-APC-Vio770, mouse

  • REA822
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-055
EUR 108,00 

CD207 (Langerin)-PerCP-Vio700, mouse

  • REA822
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-056
EUR 95,00 

CD207 (Langerin)-Biotin, mouse

  • REA822
  • 1:50
  • For research use only
30 µg in 200 µL (1)
130-113-050
EUR 32,00 

CD207 (Langerin)-Biotin, mouse

  • REA822
  • 1:50
  • For research use only
150 µg in 1 mL (1)
130-112-985
EUR 147,00